ALIMTA PACKAGE INSERT PDF

ALIMTA (pemetrexed for injection) [package insert]. Indianapolis, IN: Eli Lilly and Company; Langer CJ, et al. Lancet Oncol. ;17(11) Learn how ALIMTA may help treat advanced nonsquamous non-small cell lung cancer. ALIMTA and carboplatin (carbo) is approved by the FDA to be used with an the FDA in combination with carboplatin (another chemotherapy drug) and. Read all of this leaflet carefully before you start receiving this medicine because it contains important information for you. -. Keep this leaflet. You may need to.

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Call your doctor for medical advice about side effects. If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for ALIMTA adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity.

Low allimta cell counts. Tell your healthcare provider right away if you have a decrease in amount of urine. Severe vomiting or diarrhea can lead to loss of fluids dehydration which may cause kidney problems to become worse. It is very important to take folic acid by mouth and receive vitamin B 12 injections from your healthcare provider during packave treatment with ALIMTA to lower your risk of harmful side effects. Kidney problems, including kidney failure.

Eli Lilly and Company; Accessed June 27, Indications and Important Safety Information. NCCN makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any responsibility for their application or use in any way.

It is not known whether these effects on fertility are reversible. ALIMTA can cause severe myelosuppression resulting isert a requirement for transfusions and which may lead to neutropenic infection. For more information, ask your healthcare provider or pharmacist. Indications and Important Safety Information. ALIMTA is packwge as a single agent for the maintenance pcakage of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy.

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Males of Reproductive Potential: This may affect your ability to father a child.

ALIMTA® (Pemetrexed) and Pharmacokinetics

Continued approval for this indication may be contingent upon verification and description of clinical benefit in the confirmatory trials. Like cisplatin, carboplatin contains platinum.

Scagliotti GV, et al. Ibuprofen increases exposure AUC of pemetrexed.

There is no information regarding the presence of pemetrexed or its metabolites in human milk, the effects on the breastfed infant, or the effects inssert milk production. Based on Kaplan-Meier estimation. You are encouraged to report negative side effects of prescription drugs to the FDA. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Obtain a complete blood count at the beginning of each cycle. Go to data for additional indications. Folic acid and vitamin B 12 supplementation should be continued during treatment and for 21 days after the last dose of ALIMTA as they may reduce the severity of treatment-related hematologic and gastrointestinal toxicities. Withhold ALIMTA for acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, or fever pending diagnostic evaluation.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

This indication is approved under accelerated approval based on tumor response rate and progression-free survival. Overall response rate a ORR: Radiation recall is a skin reaction that can happen in people who have received radiation treatment in the past and are treated with ALIMTA. If you are allergic to pemetrexed, tell your packafe because you should not receive it. Advise males with female partners of reproductive potential to use effective contraception during treatment alimha ALIMTA and for 3 months after the final dose.

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It is not known if these effects are reversible.

The risk of myelosuppression is increased in patients who do not receive vitamin supplementation. Low blood cell counts can be severe, including low white blood cell counts neutropenialow platelet counts thrombocytopeniaand low red blood cell counts anemia. Hold on longer to what insett most.

Based on findings from animal studies and its mechanism of action, ALIMTA can cause fetal harm when administered to a pregnant woman.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Advanced NS NSCLC Treatment | ALIMTA (pemetrexed for injection)

Your healthcare provider may change your packag of ALIMTA, delay treatment, or stop treatment if you have certain side effects. Advise pregnant women of the potential risk to the fetus.

The incidences of Grade anemia, fatigue, thrombocytopenia, hypertension, and neutropenia were higher in patients 65 years of age and older as compared to younger patients: Talk to your healthcare provider if this is a concern for you.

Tell your healthcare provider right away if you develop blisters, skin sores, skin peeling, or painful sores, or ulcers in your mouth, nose, throat or genital area.